Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655551 | 0.90 | KDM4E (0.38) | PLAU | |
| SCHEMBL27655451 | 0.86 | PDE4A (0.45) | PDE5AEGFRPDE4APDE4BPDE4C | |
| SCHEMBL27655658 | 0.86 | ICAM1 (0.53) | ACHEAPPPDE4APDE4BPDE4C | |
| SCHEMBL27655538 | 0.85 | ACHE (0.39) | ACHEAPPEGFRPDE4APDE4B | |
| SCHEMBL27675408 | 0.84 | MEN1 (0.39) | ACHEAPPPDE5AEGFR | |
| SCHEMBL27675572 | 0.84 | ACHE (0.47) | ACHEAPPPDE5A | |
| SCHEMBL27675511 | 0.83 | PDE5A (0.41) | ACHEPDE5A | |
| SCHEMBL27655553 | 0.80 | KDM4E (0.40) | — | |
| SCHEMBL27655434 | 0.78 | KDM4E (0.42) | — | |
| SCHEMBL27675509 | 0.78 | GAA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |