Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 14/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 6/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560647 | 0.92 | KCNA5 (0.36) | KCNA5SGMS2SGMS1HCRTR2UGCG | |
| SCHEMBL2768454 | 0.84 | SMN1; SMN2 (0.40) | SGMS2MAPTMET | |
| SCHEMBL2786528 | 0.82 | HIF1A (0.36) | KCNA5SGMS2SGMS1UGCG | |
| SCHEMBL2771751 | 0.81 | TP53 (0.39) | KCNA5SGMS2SGMS1MAPT | |
| SCHEMBL2767548 | 0.80 | KCNA5 (0.36) | KCNA5SGMS2SGMS1UGCGKAT6A | |
| SCHEMBL2769801 | 0.79 | NPC1 (0.34) | KCNA5SGMS2SGMS1HCRTR2UGCG | |
| SCHEMBL2439003 | 0.79 | KDM4E (0.42) | KCNA5SGMS2SGMS1UGCGMAPT | |
| Cyclopropane SCHEMBL2441865 | 0.78 | KCNA5 (0.39) | KCNA5SGMS2SGMS1UGCGMAPT | |
| Cyclohexane SCHEMBL2442882 | 0.78 | KCNA5 (0.39) | KCNA5SGMS2SGMS1UGCGMAPT | |
| SCHEMBL2442656 | 0.76 | KCNA5 (0.40) | KCNA5SGMS2SGMS1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |