Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 12/20 | 0.35 |
| ▸ | SGMS1 | Q86VZ5 | 5/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767552 | 0.92 | KCNA5 (0.36) | KCNA5SGMS2SGMS1HCRTR2UGCG | |
| SCHEMBL3565422 | 0.83 | SMN1; SMN2 (0.42) | KCNA5SGMS2SMN1; SMN2 | |
| SCHEMBL2786528 | 0.81 | HIF1A (0.36) | KCNA5SGMS2SGMS1UGCG | |
| Cyclohexane SCHEMBL2442882 | 0.81 | KCNA5 (0.39) | KCNA5SGMS2SGMS1UGCGMAPT | |
| Cyclopropane SCHEMBL2441865 | 0.81 | KCNA5 (0.39) | KCNA5SGMS2SGMS1UGCGMAPT | |
| SCHEMBL3560643 | 0.80 | SGMS2 (0.37) | KCNA5SGMS2SGMS1SMN1; SMN2SGPL1 | |
| SCHEMBL2771751 | 0.80 | TP53 (0.39) | KCNA5SGMS2SGMS1MAPTMEN1 | |
| SCHEMBL2439003 | 0.79 | KDM4E (0.42) | KCNA5SGMS2SGMS1UGCGMAPT | |
| SCHEMBL2769801 | 0.78 | NPC1 (0.34) | KCNA5SGMS2SGMS1HCRTR2UGCG | |
| SCHEMBL2442656 | 0.77 | KCNA5 (0.40) | KCNA5SGMS2SGMS1UGCGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696238-B2 | Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics | GRUENENTHAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | GRUENENTHAL GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | KCNQ1, KCNQ2, KCNQ3 | KCNA5 38/4885SGMS2 4737/4885SGMS1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.