Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Propionate SCHEMBL4243851 | 0.85 | MAPT (0.47) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL27975739 | 0.84 | KDM4E (0.41) | SMN1; SMN2ACHEALDH1A1HPGDHSD17B10 | |
| SCHEMBL27977573 | 0.83 | ACHE (0.40) | ACHEALDH1A1HPGDHSD17B10KDM4E | |
| Ethyl Propionate SCHEMBL27418972 | 0.83 | MAPT (0.46) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2466336 | 0.79 | — | — | |
| SCHEMBL27544725 | 0.79 | MAPK1 (0.45) | ACHEALDH1A1HPGDKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL27621777 | 0.77 | — | — | |
| SCHEMBL27759265 | 0.77 | ACHE (0.41) | SMN1; SMN2ACHEHPGDMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL27363780 | 0.77 | MAPK1 (0.44) | ACHEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL27655699 | 0.75 | ALOX15 (0.41) | SMN1; SMN2ACHEALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102711813-B | Anticoagulant antidotes | BOEHRINGER INGELHEIM INT | 2015-03-04 | — | — | CN | disclosed |
| CN-103476459-A | Antidotes for anticoagulants | BOEHRINGER INGELHEIM INT | 2013-12-25 | — | — | CN | disclosed |
| CN-102711813-A | Anticoagulant antidotes | BOEHRINGER INGELHEIM INT | 2012-10-03 | — | — | CN | disclosed |
| CN-101516365-A | Inhibitors of undecaprenyl pyrophosphate synthase | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | disclosed |
| CN-1890238-A | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARM GMBH (DE) | 2007-01-03 | — | — | CN | disclosed |