Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 3/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677228 | 0.83 | RARB (0.47) | MCL1BCL2L1AKR1C2AKR1C1 | |
| SCHEMBL7050926 | 0.81 | HMGB1 (0.49) | KDM4EGAAHPGDHSD17B10MCL1 | |
| SCHEMBL11572090 | 0.80 | KDM4E (0.36) | KDM4EGAAHPGDHSD17B10MCL1 | |
| SCHEMBL27405084 | 0.80 | KDM4E (0.44) | KDM4EGAAHPGDHSD17B10MCL1 | |
| SCHEMBL2536655 | 0.80 | KDM4E (0.50) | KDM4EGAAHPGDHSD17B10HMGB1 | |
| SCHEMBL27412755 | 0.79 | KDM4E (0.42) | KDM4EGAAHPGDHSD17B10HMGB1 | |
| SCHEMBL28732291 | 0.77 | KDM4E (0.41) | KDM4EGAAHPGDHSD17B10HMGB1 | |
| SCHEMBL6100123 | 0.77 | ALDH1A1 (0.44) | KDM4EGAAHPGDHSD17B10CLCN2 | |
| SCHEMBL28733611 | 0.77 | KDM4E (0.41) | KDM4EGAAHPGDHSD17B10HMGB1 | |
| SCHEMBL28733700 | 0.77 | GABRP (0.41) | KDM4EGAAHPGDHSD17B10CLCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101018847-B | Improvements in or relating to organic compositions | RECKITT BENCKISER INC | 2011-05-11 | — | — | CN | disclosed |
| CN-101018847-A | Improvements in or relating to organic compositions | RECKITT BENCKISER INC (US) | 2007-08-15 | — | — | CN | disclosed |