Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140381 | 0.83 | IDO1 (0.44) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL20167950 | 0.83 | IDO1 (0.44) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL1429875 | 0.80 | IDO1 (0.48) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL17276025 | 0.78 | IDO1 (0.47) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL30630190 | 0.78 | TUBB1 (0.40) | ALDH1A1PTGS1MAPK1RAB9AHTT | |
| SCHEMBL30315940 | 0.78 | TUBB1 (0.40) | ALDH1A1PTGS1MAPK1RAB9AHTT | |
| SCHEMBL19756690 | 0.77 | TUBB1 (0.41) | ALDH1A1CYP3A4L3MBTL1MAPTMAPK1 | |
| SCHEMBL1429267 | 0.77 | IDO1 (0.45) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL634310 | 0.77 | ALDH1A1 (0.47) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL3365050 | 0.77 | IDO1 (0.45) | IDO1EP300KAT8ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101020628-A | Preparation method of 2, 4-difluoro-3-hydroxybenzoic acid | CHEN WEIDONG (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-101020628-A | Preparation method of 2, 4-difluoro-3-hydroxybenzoic acid | CHEN WEIDONG (CN) | 2007-08-22 | — | — | CN | disclosed |