Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL5149117 | 0.97 | NPSR1 (0.71) | NPSR1L3MBTL1ATMBACE1KMT2A | |
| Bromide SCHEMBL5149123 | 0.97 | NPSR1 (0.71) | NPSR1L3MBTL1ATMBACE1KMT2A | |
| SCHEMBL13934018 | 0.91 | NPSR1 (0.84) | NPSR1L3MBTL1ATMBACE1KMT2A | |
| Hydrochloric Acid SCHEMBL2767821 | 0.89 | NPSR1 (0.77) | NPSR1L3MBTL1ATMBACE1KMT2A | |
| Hydrochloric Acid SCHEMBL5146777 | 0.87 | NPSR1 (0.56) | NPSR1L3MBTL1ATMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1527128 | 0.86 | L3MBTL1 (0.94) | NPSR1L3MBTL1ATMBACE1KMT2A | |
| Hydrochloric Acid SCHEMBL34474900 | 0.86 | L3MBTL1 (0.94) | NPSR1L3MBTL1ATMBACE1KMT2A | |
| Bromide SCHEMBL5146810 | 0.86 | NPSR1 (0.77) | NPSR1L3MBTL1ATMKMT2AMEN1 | |
| Fluoride Ion SCHEMBL5148073 | 0.86 | NPSR1 (0.77) | NPSR1L3MBTL1ATMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2770300 | 0.85 | NPSR1 (0.71) | NPSR1L3MBTL1ATMBACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647491-B2 | Pyrophosphate-based bath for plating of tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2014-02-11 | — | — | US | claimed |
| US-20100300890-A1 | PYROPHOSPHATE-BASED BATH FOR PLATING OF TIN ALLOY LAYERS | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | claimed |
| EP-2103717-B1 | Pyrophosphate-based bath for depositing tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-04-21 | — | — | EP | claimed |
| EP-2103717-A1 | Pyrophosphate-based bath for depositing tin alloy layers | ATOTECH Deutschland GmbH (DE) | 2009-09-23 | — | — | EP | claimed |
| WO-2009109271-A2 | PYROPHOSPHATE-BASED BATH FOR PLATING ON TIN ALLOY LAYERS | ATOTECH DEUTSCHLAND GMBH (DE) | 2009-09-11 | — | — | WO | claimed |
| US-8647491-B2 | Pyrophosphate-based bath for plating of tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20100300890-A1 | PYROPHOSPHATE-BASED BATH FOR PLATING OF TIN ALLOY LAYERS | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100236936-A1 | Aqueous,alkaline,cyanide-free bath for the galvanic deposition of zinc and zinc alloy coatings | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100155257-A1 | Aqueous, alkaline, cyanide-free bath for the galvanic deposition of zinc alloy coatings | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-06-24 | — | — | US | disclosed |
| EP-2103717-B1 | Pyrophosphate-based bath for depositing tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2103717-A1 | Pyrophosphate-based bath for depositing tin alloy layers | ATOTECH Deutschland GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2009109271-A2 | PYROPHOSPHATE-BASED BATH FOR PLATING ON TIN ALLOY LAYERS | ATOTECH DEUTSCHLAND GMBH (DE) | 2009-09-11 | — | — | WO | disclosed |
| EP-2038453-A2 | AQUEOUS ALKALINE BATH, DEVOID OF CYANIDE, FOR THE DEPOSITION OF ELECTROPLATED ZINC AND ZINC ALLOY COATINGS | ATOTECH DEUTSCHLAND GMBH (DE) | 2009-03-25 | — | — | EP | disclosed |
| EP-2032742-A2 | AQUEOUS, ALKALINE BATH, DEVOID OF CYANIDE, FOR DEPOSITING ELECTROPLATED ZINC ALLOY COATINGS | ATOTECH DEUTSCHLAND GMBH (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147603-A2 | AQUEOUS ALKALINE BATH, DEVOID OF CYANIDE, FOR THE DEPOSITION OF ELECTROPLATED ZINC AND ZINC ALLOY COATINGS | ATOTECH DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007147604-A2 | AQUEOUS, ALKALINE BATH, DEVOID OF CYANIDE, FOR DEPOSITING ELECTROPLATED ZINC ALLOY COATINGS | ATOTECH DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | WO | disclosed |
| EP-1870495-A1 | Aqueous alkaline, cyanide-free, bath for the galvanic deposition of Zinc and Zinc alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2007-12-26 | — | — | EP | disclosed |