Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20260617 | 1.00 | NAAA (0.53) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL28089500 | 1.00 | NAAA (0.53) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL27657444 | 1.00 | NAAA (0.53) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL6953697 | 1.00 | NAAA (0.53) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL1538325 | 0.98 | NAAA (0.50) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL4925900 | 0.92 | ALDH1A1 (0.52) | NAAAEPHX1TSHRHCAR2ALDH1A1 | |
| SCHEMBL29873697 | 0.92 | CA12 (0.45) | NAAAEPHX1TSHRHCAR2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL21642596 | 0.90 | ALDH1A1 (0.50) | NAAAEPHX1TSHRHCAR2ALDH1A1 | |
| SCHEMBL4393654 | 0.85 | HDAC6 (0.40) | NAAAEPHX1TSHRALDH1A1 | |
| SCHEMBL19359801 | 0.85 | NAAA (0.50) | NAAAEPHX1TSHRHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930182-B | Anticoagulant compounds | SANOFI AVENTIS | 2011-11-16 | — | — | CN | disclosed |
| CN-101087622-A | Antithrombotic dual inhibitors comprising biotin residues | ORGANON NV (NL) | 2007-12-12 | — | — | CN | disclosed |
| CN-1930182-A | Anticoagulant compounds | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | CN | disclosed |