Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28154455 | 0.81 | CYP2A6 (0.72) | LMNACYP11B1CYP11B2CYP2D6CYP2A6 | |
| SCHEMBL2522379 | 0.81 | LMNA (0.62) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL1696565 | 0.81 | L3MBTL1 (0.63) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL2523376 | 0.81 | LMNA (0.62) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL4005632 | 0.81 | CYP2D6 (0.68) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL23773818 | 0.80 | L3MBTL1 (0.58) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL28171521 | 0.79 | CYP11B1 (0.66) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL2375495 | 0.78 | L3MBTL1 (0.59) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL2374361 | 0.78 | LMNA (0.58) | LMNAL3MBTL1POLBRAB9ACYP11B1 | |
| SCHEMBL27922929 | 0.78 | COMT (0.58) | LMNAL3MBTL1POLBRAB9ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101367819-B | 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof | UNIV SHANDONG | 2010-08-18 | — | — | CN | disclosed |
| CN-1958589-A | 6 (aryloxy methyl) - 2 aryl - 6, 7 dihydro 4H - pyrido [5,1 c ] [1,4] oxaxine - 4 - ketone derivative, and preparation method | UNIV SHANDONG (CN) | 2007-05-09 | — | — | CN | disclosed |