Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | FER | P16591 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indirubin SCHEMBL31032717 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL30215500 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL9899338 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL20535353 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL29361016 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL6809175 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL3857676 | 0.98 | MAOA (0.62) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL21067723 | 0.93 | MAOA (0.56) | MAOAMAOBLRRK2PDGFRAFER | |
| SCHEMBL22300581 | 0.87 | MAOA (0.50) | MAOAMAOBLRRK2PDGFRAFER | |
| SCHEMBL21440382 | 0.86 | MAOA (0.49) | MAOAMAOBLRRK2PDGFRAFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144774-A1 | CONTROLLED-RELEASE PHARMACEUTICAL COMPOSITION CONTAINING INDIGO NATURALIS OR ITS MAIN ACTIVE INGREDIENT AND PREPARATION METHOD AND USE THEREOF | Centre for Chinese Herbal Medicine Drug Development Limited (HK) | 2026-05-28 | — | — | US | claimed |
| CN-122075442-A | Controlled release pharmaceutical composition containing indigo naturalis or main active ingredient thereof, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075327-A | Scalp itching relieving composition and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070916-A | Application of arteannuin with double functions in promoting liver cell maturation and relieving liver lipid metabolism dysfunction | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-22 | — | — | CN | claimed |
| US-12618045-B2 | Automated method for preparing retinal pigment epithelium cells | CENTRE D'ETUDE DES CELLULES SOUCHES (CECS) (FR) | 2026-05-05 | — | — | US | claimed |
| US-20260085337-A1 | ENGINEERED BACTERIA TO PIGMENT POLYHYDROXYALKANOATES | NEOX PUBLIC BENEFIT LLC (US) | 2026-03-26 | — | — | US | claimed |
| EP-4713433-A2 | LIVER ORGANOIDS WITH INTRAHEPATIC SYMPATHETIC NERVES, AND METHODS OF USE THEREOF | Children's Hospital Medical Center (US) | 2026-03-25 | — | — | EP | claimed |
| EP-4689067-A2 | CLINICAL-GRADE ORGANOIDS | Children's Hospital Medical Center (US) | 2026-02-11 | — | — | EP | claimed |
| EP-2891712-B1 | METHOD FOR INDUCING PLURIPOTENT STEM CELLS TO DIFFERENTIATE INTO VENTRICULAR MYOCYTES IN VITRO | INST BIOPHYSICS CAS (CN) | 2026-01-28 | — | — | EP | claimed |
| EP-4684792-A1 | ANTIMICROBIAL AGENT AND USE THEREOF | Herzog, Artur (CH) | 2026-01-28 | — | — | EP | claimed |
| EP-0987027-A1 | Physiologically active extract | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2000-03-22 | — | — | EP | claimed |
| US-6004560-A | OBTAINING A LIQUID BY BOILING BUPLEURUM SCORZONERIFOLIUM WILLD, RADIX LASTIDIS INDIGOTICA AND FOLIUM LASTIDIS FOR A LONG TIME IN WATER, AND THEN MIXING THE LIQUID THUS OBTAINED WITH VITAMIN C | HSU WU-CHING (TW) | 1999-12-21 | — | — | US | claimed |
| CN-1202933-A | Improved microbial production of indigo | GENENCOR INT (US) | 1998-12-23 | — | — | CN | claimed |
| US-5691171-A | CULTURE OF ESCHERICHIA WITH A GENE FROM BACILLUS ENCODING PHENOL HYDROXYLASE AND DNA SEQUENCES | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1997-11-25 | — | — | US | claimed |
| WO-1997019175-A1 | IMPROVED MICROBIAL PRODUCTION OF INDIGO | GENENCOR INTERNATIONAL, INC. (US) | 1997-05-29 | — | — | WO | claimed |
| CN-1028044-C | Dye composition for dyeing denim cotton yarn and dyeing method | MITSUI TOATSU CHEMICALS (JP) | 1995-03-29 | — | — | CN | claimed |
| EP-0343925-B1 | Dye compositions for dyeing denim cotton yarns and dyeing process and dyed articles using same | MITSUI TOATSU CHEMICALS (JP) | 1994-08-31 | — | — | EP | claimed |
| US-5034016-A | Indirubin dyes, quinophthalone dyes for red, yellow, white or grey colors for cotton | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-07-23 | — | — | US | claimed |
| CN-1040642-A | Be used to dye dye composite and the dyeing and the dyed articles thereof of COARSE DRILL cloth cotton yarn | MITSUI TOATSU CHEMICALS (JP) | 1990-03-21 | — | — | CN | claimed |
| EP-0343925-A2 | Dye compositions for dyeing denim cotton yarns and dyeing process and dyed articles using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-11-29 | — | — | EP | claimed |