Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | FER | P16591 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indirubin SCHEMBL31032717 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL27678 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL20535353 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL29361016 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL6809175 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL9899338 | 1.00 | MAOA (0.64) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL3857676 | 0.98 | MAOA (0.62) | MAOAMAOBLRRK2PDGFRAFER | |
| Indirubin SCHEMBL21067723 | 0.93 | MAOA (0.56) | MAOAMAOBLRRK2PDGFRAFER | |
| SCHEMBL22300581 | 0.87 | MAOA (0.50) | MAOAMAOBLRRK2PDGFRAFER | |
| SCHEMBL21440382 | 0.86 | MAOA (0.49) | MAOAMAOBLRRK2PDGFRAFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120053467-A | Composition, pharmaceutical preparation and application thereof | 首都医科大学 | 2025-05-30 | — | — | CN | disclosed |
| US-20230100193-A1 | NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME | CYTODIGM, INC. | 2023-03-30 | — | — | US | disclosed |
| EP-4153726-A1 | METHOD FOR GENERATING FUNCTIONAL SKELETAL MUSCLE FIBERS INNERVATED BY MOTONEURONS | Association Française contre les Myopathies (AFM) (FR) | 2023-03-29 | — | — | EP | disclosed |
| CN-115768869-A | Methods of generating vascular smooth muscle cells derived from pluripotent stem cells, uses thereof, and compositions related thereto | 埃默里大学 | 2023-03-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100193-A1 | NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME | UGT2B7, UGT1A7, CYP3A7 | MAOA 543/4885MAOB 223/4885LRRK2 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.