Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.49 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | CCND1 | P24385 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16925912 | 0.89 | MEN1 (0.58) | MEN1KMT2AL3MBTL1POLBPPARG | |
| SCHEMBL16925770 | 0.82 | CDK5 (0.58) | MEN1KMT2AL3MBTL1POLBPPARG | |
| SCHEMBL8691721 | 0.77 | ERCC5 (0.54) | POLBPPARGCDK5CDK5R1DYRK1A | |
| SCHEMBL16925825 | 0.77 | GABRP (0.53) | MEN1KMT2AL3MBTL1POLBPPARG | |
| SCHEMBL16925771 | 0.76 | L3MBTL1 (0.55) | MEN1KMT2AL3MBTL1POLBPPARG | |
| SCHEMBL30900701 | 0.75 | L3MBTL1 (0.62) | MEN1KMT2AL3MBTL1MAPTKDM4E | |
| SCHEMBL16049927 | 0.75 | MAP3K11 (0.51) | MEN1KMT2AL3MBTL1POLBPPARG | |
| SCHEMBL18086412 | 0.75 | MAP3K11 (0.51) | MEN1KMT2AL3MBTL1POLBPPARG | |
| SCHEMBL7499024 | 0.74 | ERCC5 (0.50) | MEN1KMT2APPARGCDK5CDK5R1 | |
| SCHEMBL29357643 | 0.74 | GABRP (0.58) | MEN1KMT2AL3MBTL1POLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1966507-A | Benzopyran[4,3-b] indole compound, its preparation method and uses | SHANGHAI INST MATERIA MEDICA (CN) | 2007-05-23 | — | — | CN | disclosed |