SCHEMBL27679237

SCHEMBL27679237

Cc1ccc(O)c(C)c1O.[MgH2]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.46
ATM Q13315 1/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.43
TYR P14679 1/20 0.41
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 2/20 0.38
SCN5A Q14524 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
TSHR P16473 1/20 0.37
CASP1 P29466 1/20 0.37
PDE10A Q9Y233 1/20 0.37
SHBG P04278 1/20 0.37
PIM1 P11309 1/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1136903 1.00 TRPA1 (0.46) TRPA1ATMALDH1A1MEN1KMT2A
SCHEMBL21287 0.97 TRPA1 (0.48) TRPA1ATMALDH1A1MEN1KMT2A
SCHEMBL29356524 0.97 TRPA1 (0.48) TRPA1ATMALDH1A1MEN1KMT2A
SCHEMBL27679322 0.94 TRPA1 (0.46) TRPA1ATMALDH1A1MEN1KMT2A
SCHEMBL28818929 0.90 TRPA1 (0.42) TRPA1ATMALDH1A1MEN1KMT2A
P-Xylene SCHEMBL10780171 0.90 TDP1 (0.48) TRPA1ATMALDH1A1MEN1KMT2A
SCHEMBL29012437 0.85 TRPA1 (0.62) TRPA1ATMALDH1A1MEN1KMT2A
Formic Acid Methyl Ester SCHEMBL28287281 0.80 MEN1 (0.36) TRPA1ATMALDH1A1MEN1KMT2A
SCHEMBL19511951 0.80 TSHR (0.44) TRPA1ATMALDH1A1TP53TDP1
SCHEMBL23915 0.79 ALDH1A1 (0.53) TRPA1ATMALDH1A1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1934145-B Polimerization catalyst comprising an amidine ligand DSM IP ASSETS BV 2011-01-19 CN disclosed
CN-1934145-A Polimerization catalyst comprising an amidine ligand DSM IP ASSETS BV (NL) 2007-03-21 CN disclosed