SCHEMBL276795

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL276796	1.00	GRM5 (0.42)	GRM5USP7PLAUCCNA2CDK2
	SCHEMBL277330	0.82	GRM5 (0.49)	GRM5PLAUCCNA2CDK2AURKA
	SCHEMBL12755600	0.77	GRM5 (0.46)	GRM5KDM4EKDM2BKDM4CNPC1
	SCHEMBL1483831	0.77	MTOR (0.43)	GRM5SCN9AKDM2BKDM4CNPC1
	SCHEMBL12829637	0.77	MTOR (0.43)	GRM5SCN9AKDM2BKDM4CNPC1
	SCHEMBL1483834	0.77	MTOR (0.43)	GRM5SCN9AKDM2BKDM4CNPC1
	SCHEMBL277206	0.76	GRM5 (0.42)	GRM5SIGMAR1KDM2BKDM4C
	SCHEMBL277207	0.76	GRM5 (0.42)	GRM5SIGMAR1KDM2BKDM4C
	SCHEMBL1483505	0.75	MTOR (0.42)	GRM5SCN9ANPC1ALDH1A1HPGD
	SCHEMBL1483507	0.75	MTOR (0.42)	GRM5SCN9ANPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.