SCHEMBL277206

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL277207	1.00	GRM5 (0.42)	GRM5MAP3K14KMOKCNH2RIPK2
	SCHEMBL277404	0.82	GRM5 (0.49)	GRM5MAP3K14KMOKCNH2RIPK2
	SCHEMBL11907101	0.79	TMEM97 (0.38)	KMT2ASIGMAR1MEN1
	SCHEMBL12755586	0.77	RAB9A (0.46)	GRM5KDM2BKDM4CKMT2AMEN1
	SCHEMBL276795	0.76	GRM5 (0.42)	GRM5KDM2BKDM4CSIGMAR1
	SCHEMBL1483468	0.76	MEN1 (0.43)	GRM5KMOKDM2BKDM4CKMT2A
	SCHEMBL12829635	0.76	MEN1 (0.43)	GRM5KMOKDM2BKDM4CKMT2A
	SCHEMBL1483471	0.76	MEN1 (0.43)	GRM5KMOKDM2BKDM4CKMT2A
	SCHEMBL12755808	0.75	MEN1 (0.44)	GRM5KMT2AMEN1
	SCHEMBL12830103	0.75	ALDH1A1 (0.43)	KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.