Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GYS1 | P13807 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18799040 | 0.78 | MAPT (1.00) | MAPTCYP3A4LMNANPSR1CYP19A1 | |
| SCHEMBL5073672 | 0.73 | HTR7 (0.46) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL6423919 | 0.72 | CA1 (0.67) | MAPTLMNACYP19A1KDM4EALDH1A1 | |
| SCHEMBL28198 | 0.72 | CA1 (0.67) | MAPTLMNACYP19A1KDM4EALDH1A1 | |
| SCHEMBL5072019 | 0.70 | PSD (0.46) | MAPTMEN1CYP3A4KMT2ALMNA | |
| Water SCHEMBL28670631 | 0.70 | CA1 (0.64) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL6780490 | 0.70 | MAPT (0.49) | MAPTCYP1A2CYP3A4LMNANPSR1 | |
| SCHEMBL3447074 | 0.69 | MAPT (0.62) | MAPTMEN1CYP3A4KMT2ALMNA | |
| SCHEMBL527121 | 0.69 | MEN1 (0.53) | MAPTMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16472053 | 0.69 | MEN1 (0.53) | MAPTMEN1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1918133-A | Alpha-4 integrin mediated cell adhesion inhibitors for the treatment or prevention of inflammatory diseases | TANABE SEIYAKU CO (JP) | 2007-02-21 | — | — | CN | disclosed |