Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679889 | 0.70 | MAPT (0.64) | MAPTNPSR1KDM4ELMNACYP1A2 | |
| Hydrogen Sulfide SCHEMBL28172439 | 0.70 | — | — | |
| SCHEMBL1473281 | 0.69 | TDP1 (0.56) | LMNACYP1A2CYP3A4TSHRALDH1A1 | |
| SCHEMBL1907079 | 0.67 | IDO1 (0.54) | MAPTNPSR1LMNACYP3A4HPGD | |
| SCHEMBL22120275 | 0.67 | ALDH1A1 (0.61) | MAPTNPSR1KDM4EGRIN2DGRIN3B | |
| SCHEMBL11227729 | 0.66 | TTK (0.57) | MAPTKDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL17464945 | 0.65 | GRIN2D (0.44) | MAPTKDM4EGRIN2DGRIN3BLMNA | |
| SCHEMBL13164329 | 0.64 | PNP (0.44) | ALDH1A1 | |
| SCHEMBL14274453 | 0.64 | CYP1A2 (0.46) | MAPTKDM4EGRIN2DGRIN3BLMNA | |
| SCHEMBL27748904 | 0.64 | PARP1 (0.62) | MAPTGRIN2DGRIN3BLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863842-A | Entecavir midbodies and synthesis method | BRIGHTGENE BIO MEDICAL TECHNOLOGY CO LTD | 2010-10-20 | — | — | CN | disclosed |
| CN-101838270-A | Intermediates of Entecavir and preparation thereof | BRIGHTGENE BIO MEDICAL TECHNOLOGY SUZHOU CO LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-101838207-A | Intermediates of Entecavir and synthesis method thereof | BRIGHTGENE BIO MEDICAL TECHNOLOGY SUZHOU CO LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-101830856-A | Entecavir intermediates and preparation method thereof | BRIGHTGENE BIO MEDICAL TECHNOLOGY CO LTD | 2010-09-15 | — | — | CN | disclosed |
| CN-101130542-B | Synthesis of antiviral nucleoside analogues | JIANGSU CHIA TAI TIANQING PHAR | 2010-08-04 | — | — | CN | disclosed |
| CN-101130552-B | Process for preparing the antiviral agent [1s-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6h-purin-6-one | BRISTOL MYERS SQUIBB CO | 2010-07-28 | — | — | CN | disclosed |
| CN-101130542-A | Synthesis of antiviral nucleoside analogues | JIANGSU CHIA TAI TIANQING PHAR (CN) | 2008-02-27 | — | — | CN | disclosed |
| US-6673795-B2 | SUCH AS 6-(4-(4-FLUORO-PHENYL)-PIPERAZIN-1-YL)-2-METHYL-5-NITRO-3-(2,2,2-TRIFLUORO -ETHYL)-3H-PYRIMIDIN-4-ONE, WHICH ARE METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS USEFUL IN TREATING PSYCHOLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. | 2004-01-06 | — | — | US | disclosed |
| CN-1399632-A | Pyrimidine derivative, process for producing the same, and pharmaceutical containing the same as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2003-02-26 | — | — | CN | disclosed |
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |