Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.72 |
| ▸ | HPGDS | O60760 | 1/20 | 0.72 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10139147 | 0.86 | MAP4K4 (0.56) | ALKBH2HPGDSHSD11B1NPC1MAPT | |
| SCHEMBL70281 | 0.84 | ALKBH2 (1.00) | ALKBH2HPGDSEGLN1NPC1MAPT | |
| SCHEMBL2856651 | 0.83 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| SCHEMBL2860260 | 0.83 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1NPC1MAPT | |
| SCHEMBL2850367 | 0.83 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| SCHEMBL2852078 | 0.83 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| SCHEMBL28105982 | 0.82 | ALKBH2 (0.66) | ALKBH2HPGDSEGLN1HSD11B1ALKBH1 | |
| SCHEMBL15331859 | 0.81 | ALKBH2 (0.70) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| Hydrochloric Acid SCHEMBL16467067 | 0.81 | ALKBH2 (0.70) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| SCHEMBL7322694 | 0.81 | MAPKAPK2 (0.48) | ALKBH2HPGDSNPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960976-A | 4-carbox pyrazole derivates useful as anti-viral agents | SMITHKLINE BEECHAM CORP (US) | 2007-05-09 | — | — | CN | disclosed |