Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023262 | 0.88 | NPC1 (0.49) | CNR2ALDH1A1 | |
| SCHEMBL20916882 | 0.86 | NPC1 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL27680364 | 0.86 | HDAC3 (0.51) | KDM4EFFAR1 | |
| SCHEMBL1606703 | 0.83 | CA12 (0.67) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL7177997 | 0.83 | CA12 (0.46) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL28677395 | 0.83 | FLT1 (0.42) | CNR2CNR1KDM4E | |
| SCHEMBL27680468 | 0.81 | HTR2A (0.43) | HTR2AHTR2C | |
| SCHEMBL27660292 | 0.79 | CCR2 (0.47) | — | |
| SCHEMBL9023104 | 0.79 | NPC1 (0.47) | ALDH1A1 | |
| SCHEMBL27660326 | 0.79 | ALDH1A1 (0.44) | CA12CA1CA2CA9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922149-A | Pyrrole and pyrazole daao inhibitors | SEPRACOR INC (US) | 2007-02-28 | — | — | CN | disclosed |