Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102727 | 0.72 | MAPT (0.36) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL4189866 | 0.67 | MAPT (0.46) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL31144987 | 0.62 | MAPT (0.41) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL10482580 | 0.62 | MAPT (0.41) | MAPTHTTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL27297653 | 0.62 | LMNA (0.54) | SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL58073 | 0.62 | MAPT (0.51) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL10102725 | 0.61 | GAA (0.34) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL3192831 | 0.61 | MAPT (0.61) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL29105505 | 0.60 | ALDH1A1 (0.43) | MAPTHTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10102722 | 0.60 | MAPT (0.36) | MAPTHTTPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101027287-A | Method for producing 2-chloro-4-nitroimidazole | OTSUKA PHARMA CO LTD (JP) | 2007-08-29 | — | — | CN | disclosed |