Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680470 | 0.89 | DAO (0.57) | DAOGAARAB9ASMYD3NOTUM | |
| SCHEMBL875351 | 0.86 | DAO (0.54) | DAOGAARAB9ASMYD3NOTUM | |
| SCHEMBL1149656 | 0.84 | DAO (0.73) | DAOGAARAB9ANOTUM | |
| Hydrochloric Acid SCHEMBL6941257 | 0.84 | DAO (0.53) | DAOGAARAB9ASMYD3NOTUM | |
| SCHEMBL1149408 | 0.83 | DAO (0.71) | DAOGAARAB9ATDP1KDM4E | |
| SCHEMBL679780 | 0.83 | DAO (1.00) | DAOGAARAB9ANOTUM | |
| SCHEMBL1149716 | 0.83 | DAO (0.71) | DAOGAARAB9ANOTUM | |
| SCHEMBL1149419 | 0.83 | DAO (0.71) | DAOGAARAB9A | |
| SCHEMBL1225699 | 0.82 | DAO (0.60) | DAOGAARAB9ANOTUMTDP1 | |
| SCHEMBL28943248 | 0.81 | DAO (0.56) | DAOGAARAB9ANOTUMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922149-A | Pyrrole and pyrazole daao inhibitors | SEPRACOR INC (US) | 2007-02-28 | — | — | CN | disclosed |