Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 10/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858354 | 0.87 | DAO (0.77) | DAONOTUMRAB9AGAACA12 | |
| SCHEMBL1149928 | 0.85 | DAO (0.74) | DAONOTUMRAB9AKMT2A | |
| SCHEMBL13625764 | 0.85 | DAO (0.74) | DAONOTUMRAB9AGAAMEN1 | |
| SCHEMBL12704172 | 0.85 | DAO (0.73) | DAONOTUMRAB9AGAA | |
| SCHEMBL1149656 | 0.84 | DAO (0.73) | DAONOTUMRAB9AGAAMEN1 | |
| SCHEMBL1149833 | 0.84 | DAO (0.72) | DAONOTUMRAB9AGAATAAR1 | |
| SCHEMBL1149408 | 0.83 | DAO (0.71) | DAORAB9AGAAALPL | |
| SCHEMBL1149716 | 0.83 | DAO (0.71) | DAONOTUMRAB9AGAA | |
| SCHEMBL1149419 | 0.83 | DAO (0.71) | DAORAB9AGAACA12ALPL | |
| SCHEMBL27680469 | 0.83 | DAO (0.71) | DAONOTUMRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479806-B | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| CN-111479806-A | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2020-07-31 | — | — | CN | disclosed |
| WO-2019076329-A9 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-08-15 | — | — | WO | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | SEPRACOR INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | SEPRACOR INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-7488747-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-7488747-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-7488747-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2009-02-10 | — | — | US | disclosed |
| CN-1922149-A | Pyrrole and pyrazole daao inhibitors | SEPRACOR INC (US) | 2007-02-28 | — | — | CN | disclosed |
| EP-1709004-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | Sepracor Inc. (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005066135-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | SEPRACOR INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005066135-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | SEPRACOR INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050143443-A1 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | DAO, DDO, DDC | DAO 1/4885NOTUM 612/4885RAB9A 2735/4885 |
| US-20050143443-A1 | Pyrrole and pyrazole DAAO inhibitors | DDO, DAO, SRR | DAO 2/4885NOTUM 1575/4885RAB9A 2111/4885 |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | DAO 1/4885NOTUM 612/4885RAB9A 2735/4885 |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | DAO 1/4885NOTUM 612/4885RAB9A 2735/4885 |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | DDO, DAO, SRR | DAO 2/4885NOTUM 1575/4885RAB9A 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.