Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27680778

N.O=S(=O)(O)c1cccc(C=Cc2ccccc2)c1S(=O)(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
NFE2L2 Q16236 5/20 0.42
SLC16A3 O15427 1/20 0.38
NR4A1 P22736 1/20 0.38
LMNA P02545 2/20 0.38
PPARG P37231 1/20 0.38
NR1H2 P55055 1/20 0.37
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
KCNH2 Q12809 1/20 0.36
HDAC3 O15379 1/20 0.36
TNKS O95271 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285312 0.98 TRPA1 (0.47) TRPA1NFE2L2SLC16A3LMNAPPARG
SCHEMBL5145247 0.97 TRPA1 (0.46) TRPA1NFE2L2SLC16A3LMNAPPARG
SCHEMBL3936740 0.97 TRPA1 (0.46) TRPA1NFE2L2SLC16A3LMNAPPARG
SCHEMBL28578114 0.91 TRPA1 (0.41) TRPA1NFE2L2SLC16A3LMNAPPARG
SCHEMBL2799614 0.88 TRPA1 (0.39) TRPA1NFE2L2SLC16A3LMNAPPARG
Ammonia Solution, Strong SCHEMBL27722454 0.88 TRPA1 (0.50) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL8174224 0.88 TTR (0.42) NFE2L2NR4A1ALDH1A1CYP1A2CYP2D6
SCHEMBL11882514 0.86 TRPA1 (0.52) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL29725577 0.86 TRPA1 (0.52) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL1557243 0.86 TRPA1 (0.52) TRPA1NFE2L2LMNAPPARGNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101048551-B Fluorescent whitening agent composition CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2012-02-15 CN disclosed
CN-101048551-A Fluorescent whitening agent composition CIBA SC HOLDING AG (CH) 2007-10-03 CN disclosed