SCHEMBL5145247

SCHEMBL5145247

O=S(=O)(O)c1cccc(C=Cc2ccccc2)c1S(=O)(=O)O.[Na].[Na]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
NFE2L2 Q16236 5/20 0.42
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTR2A P28223 2/20 0.39
HTR2C P28335 2/20 0.39
KCNH2 Q12809 1/20 0.39
SLC16A3 O15427 1/20 0.38
HTT P42858 1/20 0.38
LMNA P02545 1/20 0.38
PPARG P37231 1/20 0.38
NR1H2 P55055 1/20 0.37
HDAC3 O15379 1/20 0.36
TNKS O95271 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285312 0.98 TRPA1 (0.47) TRPA1NFE2L2SMN1; SMN2HTR2AHTR2C
SCHEMBL3936740 0.97 TRPA1 (0.46) TRPA1NFE2L2SMN1; SMN2HTR2AHTR2C
Ammonia Solution, Strong SCHEMBL27680778 0.97 TRPA1 (0.46) TRPA1NFE2L2SMN1; SMN2HTR2AHTR2C
SCHEMBL28578114 0.91 TRPA1 (0.41) TRPA1NFE2L2HTR2AHTR2CKCNH2
SCHEMBL2799614 0.88 TRPA1 (0.39) TRPA1NFE2L2HTR2AHTR2CKCNH2
SCHEMBL8174224 0.88 TTR (0.42) NFE2L2TSHRSMN1; SMN2HTT
SCHEMBL11882514 0.86 TRPA1 (0.52) TRPA1NFE2L2TSHRSMN1; SMN2HTR2A
SCHEMBL29725577 0.86 TRPA1 (0.52) TRPA1NFE2L2TSHRSMN1; SMN2HTR2A
SCHEMBL1557243 0.86 TRPA1 (0.52) TRPA1NFE2L2TSHRSMN1; SMN2HTR2A
SCHEMBL4207529 0.86 TRPA1 (0.52) TRPA1NFE2L2TSHRSMN1; SMN2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687101-A4 VEHICLE IDENTIFICATION MARKING SYSTEM RODRIGUEZ MILTON (US) 2007-08-08 EP disclosed
EP-1687101-A2 VEHICLE IDENTIFICATION MARKING SYSTEM Rodriguez, Milton (US) 2006-08-09 EP disclosed
WO-2005051718-A2 VEHICLE IDENTIFICATION MARKING SYSTEM RODRIGUEZ MILTON (US) 2005-06-09 WO disclosed
EP-1246899-A1 PRO-PERFUME COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2002-10-09 EP disclosed
EP-1117757-A1 LAUNDRY DETERGENT AND/OR FABRIC CARE COMPOSITIONS COMPRISING A CHEMICAL ENTITY, WHICH CONTAINS A DEPOSITION AID, AND A POLYMER THE PROCTER & GAMBLE COMPANY (US) 2001-07-25 EP disclosed
WO-2001051599-A1 PRO-PERFUME COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2001-07-19 WO disclosed
WO-2000018865-A1 LAUNDRY DETERGENT AND/OR FABRIC CARE COMPOSITIONS COMPRISING A CHEMICAL ENTITY, WHICH CONTAINS A DEPOSITION AID, AND A POLYMER THE PROCTER & GAMBLE COMPANY (US) 2000-04-06 WO disclosed
WO-1997045513-A9 DETERGENT COMPOSITION 1998-03-12 WO disclosed
WO-1995025159-A1 BLEACH IMPROVEMENT WITH MANGANESE ETHYLENEDIAMINE-N,N'-DISUCCINATE THE PROCTER & GAMBLE COMPANY (US) 1995-09-21 WO disclosed
EP-0405967-A2 Built liquid detergent compositions Amway Corporation (US) 1991-01-02 EP disclosed
EP-0385562-A2 Laundry detergent composition Amway Corporation (US) 1990-09-05 EP disclosed