Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28312942 | 0.70 | KCNN4 (0.57) | KCNN4LMNAHTTL3MBTL1CYP2C19 | |
| SCHEMBL20738658 | 0.68 | KCNN4 (0.55) | KCNN4CYP2C19HIF1AHDAC1HDAC3 | |
| SCHEMBL2102971 | 0.67 | KCNN4 (0.53) | KCNN4LMNAHTTL3MBTL1NR3C2 | |
| SCHEMBL8142427 | 0.65 | KCNN4 (0.61) | KCNN4LMNAHTTL3MBTL1CYP2C19 | |
| SCHEMBL28583517 | 0.65 | HDAC3 (0.41) | KCNN4CYP2C19HIF1AHDAC1HDAC3 | |
| SCHEMBL27546025 | 0.65 | KCNN4 (0.50) | KCNN4LMNAHTTL3MBTL1KMT2A | |
| SCHEMBL11805262 | 0.64 | KCNN4 (0.67) | KCNN4CYP2C19HIF1ANR3C2ALDH1A1 | |
| SCHEMBL3326124 | 0.64 | KCNN4 (0.67) | KCNN4CYP2C19HIF1ANR3C2ALDH1A1 | |
| SCHEMBL2490805 | 0.64 | KCNN4 (1.00) | KCNN4NR3C2ALDH1A1 | |
| SCHEMBL27776663 | 0.64 | KCNN4 (0.59) | KCNN4LMNAHTTL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039701-A | Prodrugs and codrug comprising a biocleavable disulfide linker | NICHOLAS PIRAMAL INDIA LTD (IN) | 2007-09-19 | — | — | CN | disclosed |