Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338695 | 0.89 | GFER (0.48) | ACACBDYRK1AHPGDBCHEACHE | |
| SCHEMBL13402936 | 0.79 | DYRK1A (0.48) | ACACBDYRK1AHPGDUSP2SMN1; SMN2 | |
| SCHEMBL28070878 | 0.76 | MAPK8 (0.52) | DYRK1AHPGDSMN1; SMN2ACHERBP4 | |
| SCHEMBL25591594 | 0.76 | GPR119 (0.48) | ACHE | |
| SCHEMBL28087268 | 0.75 | MAPK8 (0.54) | DYRK1AHPGDSMN1; SMN2ACHERBP4 | |
| SCHEMBL26141096 | 0.75 | ACACB (0.46) | ACACBDYRK1AHPGDUSP2SMN1; SMN2 | |
| SCHEMBL13384566 | 0.75 | ACACB (0.46) | ACACBDYRK1AHPGDUSP2SMN1; SMN2 | |
| SCHEMBL26141087 | 0.75 | ACACB (0.46) | ACACBDYRK1AHPGDUSP2SMN1; SMN2 | |
| SCHEMBL7018239 | 0.74 | GFER (0.43) | HPGDUSP2SMN1; SMN2BCHEACHE | |
| SCHEMBL5778634 | 0.74 | SMN1; SMN2 (0.48) | DYRK1AHPGDUSP2SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |