Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL27682008

CCO.N.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EPHX1 P07099 1/20 0.37
TSHR P16473 2/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL27910342 0.97 ALDH1A1 (0.39) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL29171770 0.94 ALDH1A1 (0.38) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL2958868 0.88 EPHX1 (0.41) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL2285727 0.88 ALDH1A1 (0.41) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL3361058 0.85 EPHX1 (0.43) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL27669034 0.85 ALDH1A1 (0.39) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL1851236 0.85 ALDH1A1 (0.39) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL10776345 0.84 ALDH1A1 (0.43) ALDH1A1L3MBTL1EPHX1TSHRCA1
Trifluoromethanesulfonic Acid SCHEMBL11049559 0.84 ALDH1A1 (0.47) ALDH1A1L3MBTL1TSHRCA1CA2
Trifluoromethanesulfonic Acid SCHEMBL137559 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1997620-A Ionic liquids comprising nitrogen-containing cations UNIV YORK (GB) 2007-07-11 CN claimed
CN-1997620-B Ionic liquids comprising nitrogen-containing cations UNIV YORK 2012-10-03 CN disclosed
CN-102344379-A Ionic liquid containing nitrogen-containing cation UNIV YORK 2012-02-08 CN disclosed
CN-1997620-A Ionic liquids comprising nitrogen-containing cations UNIV YORK (GB) 2007-07-11 CN disclosed