SCHEMBL27682149

SCHEMBL27682149

C1=Cc2ccccc2NN=C1CCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
KCNH2 Q12809 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
MAOA P21397 3/20 0.33
MAOB P27338 3/20 0.33
NISCH Q9Y2I1 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
MGLL Q99685 1/20 0.33
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8642184 0.80 KEAP1 (0.41) GAAMAPTALDH1A1CYP1A2CYP2C9
SCHEMBL4481007 0.79 MAPT (0.42) GAAMAPTKCNH2ALDH1A1CYP3A4
SCHEMBL8696697 0.77 GAA (0.43) GAAMAPTHTR2A
SCHEMBL11710279 0.77 GAA (0.43) GAAMAPT
SCHEMBL9934042 0.77 GAA (0.43) GAAMAPT
SCHEMBL8552747 0.77 GAA (0.43) GAAMAPT
SCHEMBL27943725 0.76 GAA (0.40) GAAMAPTKCNH2ALDH1A1NPC1
SCHEMBL28100450 0.76 GAA (0.40) GAAMAPTKCNH2ALDH1A1NPC1
SCHEMBL4717203 0.75 GAA (0.38) GAAMAPTALDH1A1RAB9ACASP1
Hydrazine SCHEMBL28113327 0.74 GAA (0.38) GAAMAPTKCNH2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102552085-B Compositions containing bermuda lily (LILIUM CANDIDUM) extract and application thereof 强生消费者公司 2016-12-28 CN disclosed
CN-106038351-A Polypeptide composition for smoothing wrinkles 深圳市维琪医药研发有限公司 2016-10-26 CN disclosed
CN-101084862-B Compositions containing a hydroxylated diphenylmethane compound OREAL 2011-04-27 CN disclosed
CN-101084862-A Compositions containing a hydroxylated diphenylmethane compound OREAL (FR) 2007-12-12 CN disclosed