Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28100450 | 0.97 | GAA (0.40) | GAAMAPTLIPGKCNH2TLR8 | |
| SCHEMBL27943725 | 0.97 | GAA (0.40) | GAAMAPTLIPGKCNH2TLR8 | |
| SCHEMBL8900868 | 0.77 | GAA (0.38) | GAAMAPTTLR8ALDH1A1 | |
| SCHEMBL5937307 | 0.74 | L3MBTL1 (0.36) | KCNH2NPC1ALDH1A1GPR84 | |
| SCHEMBL4788944 | 0.71 | KCNH3 (0.38) | GAAMAPTNPC1ALDH1A1 | |
| Benzodiazepine SCHEMBL8530199 | 0.70 | GAA (0.34) | GAAMAPTLIPGKCNH2GPR3 | |
| Anthracene SCHEMBL28851492 | 0.69 | TLR8 (0.40) | MAPTTLR8ALDH1A1 | |
| SCHEMBL11666346 | 0.69 | GAA (0.33) | GAAMAPT | |
| SCHEMBL8197993 | 0.69 | MAPT (0.37) | GAAMAPTALDH1A1 | |
| SCHEMBL7492328 | 0.68 | GAA (0.39) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520272-B | Donepezil derivant | SUZHOU SHANGZHI BIOTECH LTD. (CN) | 2016-11-30 | — | — | CN | disclosed |