Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701390 | 0.83 | POLB (0.48) | POLBNPSR1ALDH1A1TAAR1LMNA | |
| SCHEMBL4597752 | 0.77 | POLB (0.42) | POLBNPSR1ALDH1A1KDM4ETAAR1 | |
| SCHEMBL5173306 | 0.71 | POLB (0.47) | POLBNPSR1ALDH1A1KDM4ETAAR1 | |
| SCHEMBL12555524 | 0.68 | POLB (0.65) | POLBNPSR1ALDH1A1TAAR1LMNA | |
| SCHEMBL5930625 | 0.66 | POLB (0.41) | POLBNPSR1ALDH1A1TAAR1LMNA | |
| SCHEMBL1260201 | 0.63 | ALDH1A1 (0.43) | POLBNPSR1ALDH1A1TAAR1LMNA | |
| SCHEMBL12855057 | 0.63 | POLB (0.45) | POLBNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL31306437 | 0.63 | NLRP3 (0.44) | POLBNPSR1ALDH1A1KDM4ETAAR1 | |
| SCHEMBL5172909 | 0.63 | POLB (0.48) | POLBNPSR1ALDH1A1TAAR1LMNA | |
| SCHEMBL1261039 | 0.62 | ALDH1A1 (0.45) | POLBNPSR1ALDH1A1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087780-A | Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs | BAYER SCHERING PHARMA AG (DE) | 2007-12-12 | — | — | CN | disclosed |