Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218320 | 0.85 | THRB (0.46) | THRBMTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL183158 | 0.85 | THRB (0.44) | THRBMTNR1AMTNR1BTSHRKMT2A | |
| SCHEMBL5355849 | 0.84 | THRB (0.53) | THRBMTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL30308292 | 0.84 | THRB (0.57) | THRBMTNR1AMTNR1BTSHRKMT2A | |
| SCHEMBL3053163 | 0.83 | THRB (0.44) | THRBMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL1523936 | 0.83 | THRB (0.43) | THRBMTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL125488 | 0.83 | THRB (0.43) | THRBMTNR1AMTNR1BTSHRMAPT | |
| Ether SCHEMBL7078862 | 0.82 | THRB (0.43) | THRBMTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL9337651 | 0.81 | THRB (0.47) | THRBMTNR1AMTNR1BTSHRLMNA | |
| SCHEMBL9491739 | 0.81 | THRB (0.43) | THRBTSHRTDP1THRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569013-B1 | Curable composition for optical parts | NIPPON CATALYTIC CHEM IND (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-20070049655-A1 | Radiation-curable composition and cured product thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| US-20050192373-A1 | Curable composition for optical parts | NIPPON SHOKUBAI CO., LTD. | 2005-09-01 | — | — | US | disclosed |
| EP-1569013-A2 | Curable composition for optical parts | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |