Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928684 | 0.88 | FLT3 (0.52) | FLT3MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL27682865 | 0.87 | FLT3 (0.46) | FLT3RAB9ANPC1POLBDRD3 | |
| SCHEMBL27663292 | 0.86 | NPC1 (0.46) | FLT3RAB9ANPC1POLBKDM4E | |
| SCHEMBL6661201 | 0.76 | FLT3 (0.58) | FLT3MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL3924095 | 0.75 | FLT3 (0.47) | FLT3DRD3DRD4KDM4EALDH1A1 | |
| SCHEMBL3923810 | 0.75 | KDM4E (0.53) | FLT3RAB9ANPC1KDM4EMEN1 | |
| SCHEMBL3935357 | 0.74 | MEN1 (0.47) | FLT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL27683032 | 0.74 | FLT3 (0.53) | FLT3RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL6657213 | 0.72 | FLT3 (0.54) | FLT3MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL3924063 | 0.71 | PDGFRB (0.46) | MTNR1AMTNR1BDRD2DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989103-A | Indole-2-carboxamidine derivatives as NMDA receptor antagonists | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | claimed |