Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928751 | 0.88 | FLT3 (0.52) | FLT3KDM4EALDH1A1MEN1MAPT | |
| SCHEMBL27682863 | 0.87 | FLT3 (0.46) | FLT3KDM4EALDH1A1HPGD | |
| SCHEMBL27663289 | 0.86 | MEN1 (0.46) | FLT3MEN1RAB9AKMT2APDGFRB | |
| SCHEMBL3924098 | 0.75 | FLT3 (0.47) | FLT3KDM4EALDH1A1HPGD | |
| SCHEMBL3923816 | 0.75 | PDGFRB (0.50) | FLT3MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL3935363 | 0.74 | MEN1 (0.47) | FLT3MEN1RAB9AKMT2A | |
| SCHEMBL27683033 | 0.74 | FLT3 (0.53) | FLT3KDM4EALDH1A1MEN1MAPT | |
| SCHEMBL3924069 | 0.71 | GRIN1 (0.48) | KDM4EPDGFRBPDGFRAGAA | |
| SCHEMBL3928684 | 0.71 | FLT3 (0.52) | FLT3KDM4EALDH1A1MEN1MAPT | |
| SCHEMBL6661201 | 0.71 | FLT3 (0.58) | FLT3KDM4EALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989103-A | Indole-2-carboxamidine derivatives as NMDA receptor antagonists | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | claimed |