SCHEMBL27683039

SCHEMBL27683039

CC(C)OC(C)C.O=C(c1ccccc1)c1ccccc1CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
ELANE P08246 3/20 0.43
GAA P10253 2/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 1/20 0.43
CYP19A1 P11511 1/20 0.43
MAPT P10636 2/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
BCL2 P10415 1/20 0.41
MCL1 Q07820 1/20 0.41
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
POLB P06746 1/20 0.40
ABCB1 P08183 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL28769085 0.87 AKR1C3 (0.50) AKR1C3L3MBTL1ELANEGAAHPGD
SCHEMBL29898649 0.87 AKR1C3 (0.57) AKR1C3L3MBTL1GAAHPGDLMNA
SCHEMBL417620 0.87 AKR1C3 (0.57) AKR1C3L3MBTL1GAAHPGDLMNA
SCHEMBL27703158 0.85 ALDH1A1 (0.45) AKR1C3L3MBTL1ELANEGAAHPGD
SCHEMBL31414970 0.85 AKR1C3 (0.55) AKR1C3L3MBTL1GAAHPGDLMNA
Benzophenone SCHEMBL9308337 0.79 ALDH1A1 (0.64) L3MBTL1ELANEHPGDLMNAMAPT
Maleic Acid SCHEMBL11227321 0.79 AKR1C3 (0.48) AKR1C3L3MBTL1GAAHPGDLMNA
Fumaric Acid SCHEMBL11348511 0.79 AKR1C3 (0.48) AKR1C3L3MBTL1GAAHPGDLMNA
SCHEMBL27892411 0.78 TSHR (0.46) AKR1C3L3MBTL1GAARAB9ANPC1
SCHEMBL6072641 0.77 AKR1C3 (0.50) AKR1C3L3MBTL1ELANEGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101038449-B Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH CO LTD 2011-06-01 CN disclosed
CN-100478711-C Active energy beam curing resin composition and sheet-form optical article MITSUBISHI RAYON CO (JP) 2009-04-15 CN disclosed
CN-101044418-A Active energy beam curing resin composition and sheet-form optical article MITSUBISHI RAYON CO (JP) 2007-09-26 CN disclosed
CN-101038449-A Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH KK (JP) 2007-09-19 CN disclosed