Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682913 | 0.89 | SLC6A2 (0.38) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL2073879 | 0.85 | CACNA2D1 (0.39) | SLC6A2SLC6A4 | |
| SCHEMBL2073143 | 0.74 | SLC6A2 (0.39) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL2072820 | 0.73 | SLC6A2 (0.46) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2072824 | 0.73 | SLC6A2 (0.46) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27663375 | 0.65 | ADRA2A (0.35) | SLC6A2SLC6A4SLC6A3NR3C1 | |
| SCHEMBL27682977 | 0.64 | SLC6A2 (0.36) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2073982 | 0.61 | SLC6A2 (0.47) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2762659 | 0.61 | GAA (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1MKNK1 | |
| SCHEMBL21917569 | 0.61 | CACNA2D1 (0.50) | MEN1KMT2APOLBMCHR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993321-A | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |