Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.39 |
| ▸ | SI | P14410 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071176 | 0.82 | SLC6A4 (0.64) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL27663380 | 0.81 | GPR84 (0.49) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL27663374 | 0.80 | HTR2A (0.43) | LMNAHTTMEN1KMT2AMAPT | |
| SCHEMBL2071173 | 0.80 | SLC6A4 (0.49) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL2071174 | 0.80 | UBE2N (0.50) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL5261217 | 0.80 | UBE2N (0.46) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL14667574 | 0.77 | ALDH1A1 (0.53) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL7939769 | 0.76 | GAA (0.45) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL7952652 | 0.75 | ALDH1A1 (0.45) | UBE2NALDH1A1LMNAHTTMEN1 | |
| SCHEMBL1423207 | 0.75 | MEN1 (0.45) | UBE2NALDH1A1LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993321-A | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |