Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL9445395 | 0.92 | POLB (0.55) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL17939 | 0.91 | IDO1 (0.59) | MTNR1AMTNR1BALDH1A1HTTL3MBTL1 | |
| Methyl Alcohol SCHEMBL11157987 | 0.89 | IDO1 (0.57) | MTNR1AMTNR1BALDH1A1SMN1; SMN2HTT | |
| Ammonia Solution, Strong SCHEMBL265951 | 0.89 | IDO1 (0.57) | MTNR1AMTNR1BALDH1A1HTTL3MBTL1 | |
| SCHEMBL21395 | 0.88 | IDO1 (0.52) | MTNR1AMTNR1BALDH1A1SMN1; SMN2HTT | |
| 1,2-Dimethoxybenzene SCHEMBL27679751 | 0.82 | CA1 (0.72) | KMT2AALDH1A1NPC1RAB9APOLB | |
| SCHEMBL710329 | 0.82 | LMNA (0.56) | MTNR1AMTNR1BMEN1KMT2ANPC1 | |
| SCHEMBL29431297 | 0.82 | HSD17B10 (0.61) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL155982 | 0.82 | HSD17B10 (0.61) | MEN1KMT2ANPC1RAB9APOLB | |
| Bicarbonate SCHEMBL5277147 | 0.81 | IDO1 (0.55) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103764689-A | Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer | TOHO TITANIUM CO LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-101044109-B | Industrial process for production of high-purity diaryl carbonate | ASAHI CHEMICAL CORP (JP) | 2011-07-06 | — | — | CN | disclosed |
| CN-101039896-B | Process for production of high-purity diaryl carbonate | ASAHI CHEMICAL IND (JP) | 2011-06-22 | — | — | CN | disclosed |
| CN-101044109-A | Industrial process for production of high-purity diaryl carbonate | ASAHI CHEMICAL CORP (JP) | 2007-09-26 | — | — | CN | disclosed |
| CN-101039896-A | Process for production of high-purity diaryl carbonate | ASAHI CHEMICAL CORP (JP) | 2007-09-19 | — | — | CN | disclosed |