Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16335080 | 0.85 | TAAR1 (0.53) | TAAR1IDO1AGXTFFAR1FFAR4 | |
| SCHEMBL4234560 | 0.85 | ALDH1A1 (0.60) | TAAR1FFAR1FFAR4MAOBESR1 | |
| SCHEMBL4399626 | 0.80 | TAAR1 (0.74) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL7332798 | 0.80 | TAAR1 (0.57) | TAAR1IDO1AGXTFFAR1FFAR4 | |
| SCHEMBL9294120 | 0.79 | TAAR1 (0.50) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL3455973 | 0.78 | TAAR1 (0.55) | TAAR1IDO1AGXTFFAR1FFAR4 | |
| SCHEMBL6586 | 0.78 | FFAR1 (0.68) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL8175846 | 0.78 | TAAR1 (0.55) | TAAR1IDO1AGXTFFAR1FFAR4 | |
| SCHEMBL3397240 | 0.78 | TAAR1 (0.50) | TAAR1FFAR1FFAR4MAOBESR1 | |
| SCHEMBL31265910 | 0.78 | APP (0.51) | TAAR1FFAR1FFAR4ESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296897-A | PPAR-modulating biaromatic compounds | GALDERMA RES & DEV (FR) | 2008-10-29 | — | — | CN | disclosed |
| CN-1950335-A | Novel biaromatic compounds which activate PPAR.gamma.-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-04-18 | — | — | CN | disclosed |