SCHEMBL27683293

SCHEMBL27683293

C=CC(=O)NC(O)(CC)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TSHR P16473 3/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
PSMB11 A5LHX3 1/20 0.33
PSMA7 O14818 1/20 0.33
PSMB1 P20618 1/20 0.33
PSMA1 P25786 1/20 0.33
PSMA2 P25787 1/20 0.33
PSMA3 P25788 1/20 0.33
PSMA4 P25789 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB9 P28065 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL27767619 0.98 ALDH1A1 (0.35) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL10489512 0.81 ALDH1A1 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL246454 0.75 ALDH1A1 (0.39) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Methoxymethane SCHEMBL28057078 0.73 ALDH1A1 (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL8027978 0.73 TSHR (0.34) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL3319888 0.72 ALDH1A1 (0.40) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL26478897 0.72 ALDH1A1 (0.40) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL17350190 0.72 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL4792294 0.72 DGAT1 (0.45) ALDH1A1TDP1KDM4EPKMMEN1
SCHEMBL29383045 0.72 DGAT1 (0.45) ALDH1A1TDP1KDM4EPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101687397-A Elastomeric items with desirable strength and comfort properties BANGKOK SYNTHETICS CO LTD 2010-03-31 CN disclosed
CN-101056931-A Process for preparing silicone-modified polymers WACKER CHEMIE AG (DE) 2007-10-17 CN disclosed