Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627243 | 0.84 | ESR1 (0.47) | MAPTGAATSHRALOX15HSD17B10 | |
| SCHEMBL4080385 | 0.78 | ALDH1A1 (0.48) | MAPTTSHRHPGDTHRBHSD17B10 | |
| SCHEMBL27473286 | 0.76 | LMNA (0.60) | MAPTGAATSHRHPGDALOX15 | |
| SCHEMBL27683522 | 0.76 | CA12 (0.42) | MAPTGAATSHRHPGDALOX15 | |
| SCHEMBL3794319 | 0.76 | PLK1 (0.54) | MAPTGAATSHRHPGDALOX15 | |
| SCHEMBL6199448 | 0.72 | CYP3A4 (0.36) | MAPTGAATSHRRECQLALDH1A1 | |
| SCHEMBL3391137 | 0.72 | HPGD (0.58) | MAPTGAATSHRHPGDAPP | |
| SCHEMBL28989702 | 0.71 | PLK1 (0.45) | MAPTGAAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL28005093 | 0.71 | PLK1 (0.45) | MAPTGAAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL5356617 | 0.69 | ALDH1A1 (0.54) | MAPTGAAHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101080669-A | Low refractive index polymers as underlayers for silicon-containing photoresists | IBM (US) | 2007-11-28 | — | — | CN | disclosed |