Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138444 | 0.86 | KCNMA1 (0.56) | KCNMA1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7496493 | 0.84 | KCNMA1 (0.64) | KCNMA1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10224040 | 0.82 | KCNMA1 (0.55) | KCNMA1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL249599 | 0.78 | KCNMA1 (0.56) | KCNMA1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL10224079 | 0.78 | KCNMA1 (0.56) | KCNMA1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10223864 | 0.78 | P2RX1 (0.65) | KCNMA1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18585890 | 0.77 | KCNMA1 (0.67) | KCNMA1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL7253753 | 0.76 | KCNMA1 (0.57) | KCNMA1MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL7253758 | 0.76 | KCNMA1 (0.57) | KCNMA1MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL5357012 | 0.76 | KCNMA1 (0.68) | KCNMA1NPC1LMNAL3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101142184-A | Sulfonamide peri-substituted bicyclics for occlusive artery disease | DECODE GENETICS INC (IS) | 2008-03-12 | — | — | CN | disclosed |
| CN-101076531-A | Carboxylic acid peri-substituted bicyclics for occlusive artery disease | DECODE CHEMISTRY INC (US) | 2007-11-21 | — | — | CN | disclosed |