Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.51 |
| ▸ | PDE4A | P27815 | 4/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823187 | 0.92 | LMNA (0.55) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4826806 | 0.87 | PDE4D (0.53) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4822401 | 0.83 | PDE4A (0.61) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4823564 | 0.83 | PDE4D (0.57) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7183447 | 0.83 | PDE4A (0.64) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL628797 | 0.81 | LMNA (0.56) | LMNAHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4825458 | 0.81 | PDE4A (0.53) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4825769 | 0.81 | PDE4D (0.64) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7172764 | 0.80 | PDE4A (0.55) | LMNAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4818631 | 0.79 | PDE4A (0.55) | LMNAPDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101053558-A | Diphenylethylene compounds and uses thereof | CELGENE CORP (US) | 2007-10-17 | — | — | CN | disclosed |