Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 5/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685121 | 0.95 | PSIP1 (0.39) | PSIP1MCHR1ALDH1A1OPRM1OPRD1 | |
| SCHEMBL27685273 | 0.92 | PSIP1 (0.37) | PSIP1MCHR1ALDH1A1 | |
| SCHEMBL27704279 | 0.87 | PSIP1 (0.43) | PSIP1KDM4EALDH1A1FABP3FABP4 | |
| SCHEMBL27685128 | 0.86 | ADRA2A (0.46) | PSIP1KDM4EBRD4 | |
| SCHEMBL28765418 | 0.83 | PSIP1 (0.42) | PSIP1KDM4EALDH1A1FABP3FABP4 | |
| SCHEMBL27703975 | 0.82 | PSIP1 (0.38) | PSIP1MCHR1 | |
| SCHEMBL27704120 | 0.80 | PSIP1 (0.44) | PSIP1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2821958 | 0.79 | FABP3 (0.43) | MCHR1KDM4EALDH1A1FABP3FABP4 | |
| SCHEMBL27703964 | 0.79 | KDM4E (0.46) | PSIP1KDM4EALDH1A1RXFP1LMNA | |
| SCHEMBL27703955 | 0.77 | PSIP1 (0.41) | PSIP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068788-A | As GABABQuinoline compounds as allosteric enhancers of receptors | HOFFMANN LA ROCHE (CH) | 2007-11-07 | — | — | CN | claimed |
| CN-101068788-A | As GABABQuinoline compounds as allosteric enhancers of receptors | HOFFMANN LA ROCHE (CH) | 2007-11-07 | — | — | CN | disclosed |