Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MGAM | O43451 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SI | P14410 | 2/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801141 | 0.76 | MAPT (0.51) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL14936927 | 0.74 | MAPT (0.62) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL5328162 | 0.73 | NPC1 (1.00) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL30036439 | 0.72 | MAOB (0.63) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL103158 | 0.72 | MAOB (0.63) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL28073111 | 0.71 | RAB9A (0.52) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL23699969 | 0.70 | NPC1 (0.53) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| Methane SCHEMBL28188109 | 0.69 | MAOB (0.61) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL30561833 | 0.69 | MAOB (0.55) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL2930650 | 0.69 | CYP19A1 (0.56) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101037445-A | Imidazo [2,1-b]-1,3,4-thiadiazole derivatives having potential biological activity and synthesizing method thereof | UNIV NORTHWEST NORMAL (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-101037445-A | Imidazo [2,1-b]-1,3,4-thiadiazole derivatives having potential biological activity and synthesizing method thereof | UNIV NORTHWEST NORMAL (CN) | 2007-09-19 | — | — | CN | disclosed |