Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30036439 | 1.00 | MAOB (0.63) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL2150499 | 0.95 | MAOB (0.59) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL2149640 | 0.93 | MAOB (0.57) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL7125605 | 0.87 | MAOB (0.68) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL12854020 | 0.85 | MAOB (0.71) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL30561833 | 0.85 | MAOB (0.55) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL61411 | 0.85 | MAOB (0.71) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL731363 | 0.85 | MAOB (0.71) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL31105656 | 0.85 | MAOB (0.71) | MAOBMAOAALOX5NPC1RAB9A | |
| SCHEMBL4659168 | 0.85 | MAOB (0.78) | MAOBMAOAALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966166-B1 | 1,2,4-TRIAZOL-l-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMOURS | STERIX LTD (GB) | 2013-01-23 | — | — | EP | claimed |
| US-8124584-B2 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-28 | — | — | US | claimed |
| US-20090304629-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | MIAO ZHENWEI | 2009-12-10 | — | — | US | claimed |
| US-7601709-B2 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | claimed |
| EP-1590442-A4 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARM INC (US) | 2007-07-18 | — | — | EP | claimed |
| EP-1590442-A3 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2005-11-03 | — | — | EP | claimed |
| EP-1590442-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2005-11-02 | — | — | EP | claimed |
| US-20050153877-A1 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. | 2005-07-14 | — | — | US | claimed |
| WO-2004072243-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2004-08-26 | — | — | WO | claimed |
| WO-2001025212-A2 | CYCLIC BIPHENYLS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS | MORPHOCHEM AG (DE) | 2001-04-12 | — | — | WO | claimed |
| US-20260124571-A1 | SYSTEMS AND METHODS FOR REMOVING ORGANIC COMPOUNDS FROM THE OUTPUT OF PYROLYSIS OR OTHER REACTORS | MODERN HYDROGEN INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260055126-A1 | SMALL MOLECULE COMPOUNDS WITH PHOSPHORYLATED ARYL STRUCTURES AND USE THEREOF | HANGZHOU PHECDAMED CO LTD (CN) | 2026-02-26 | — | — | US | disclosed |
| US-12491466-B2 | Systems and methods for removing organic compounds from the output of pyrolysis or other reactors | MODERN HYDROGEN, INC. (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250332559-A1 | SYSTEMS AND METHODS FOR COOLING AND SEPARATING CO-PRODUCTS FROM A PYROLYSIS SYSTEM | MODERN HYDROGEN INC (US) | 2025-10-30 | — | — | US | disclosed |
| EP-4635958-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2001025213-A2 | PYRROLO IMIDAZOLE DERIVATIVES AND THEIR USE AS MEDICAMENTS | MORPHOCHEM AG (DE) | 2001-04-12 | — | — | WO | disclosed |
| EP-0983290-A1 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | Morphochem AG (DE) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998051697-A2 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | MORPHOCHEM AG (DE) | 1998-11-19 | — | — | WO | disclosed |
| EP-0422329-B1 | Substituted dibenzofurans and methods of using same | EURO CELTIQUE SA (LU) | 1995-07-26 | — | — | EP | disclosed |
| EP-0422329-A1 | Substituted dibenzofurans and methods of using same | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153877-A1 | Macrocyclic hepatitis C serine protease inhibitors | PRSS1, SPINT2, TMPRSS4 | MAOB 1631/4885MAOA 1985/4885ALOX5 2702/4885 |
| US-20260055126-A1 | SMALL MOLECULE COMPOUNDS WITH PHOSPHORYLATED ARYL STRUCTURES AND USE THEREOF | YAP1, YES1, NCOA1 | MAOB 3810/4885MAOA 4123/4885ALOX5 4064/4885 |
| US-20090304629-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, SPINT2, TMPRSS4 | MAOB 1601/4885MAOA 2007/4885ALOX5 2889/4885 |
| US-20260124571-A1 | SYSTEMS AND METHODS FOR REMOVING ORGANIC COMPOUNDS FROM THE OUTPUT OF PYROLYSIS OR OTHER REACTORS | FH, PORCN, MCCC2 | MAOB 2957/4885MAOA 1910/4885ALOX5 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.