Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122068 | 0.89 | KMT2A (0.54) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL10311200 | 0.83 | KMT2A (0.51) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL8340951 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL3407704 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL255037 | 0.79 | NOTUM (0.50) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL21859763 | 0.79 | SLC6A2 (0.52) | ALDH1A1KMT2AMEN1NOTUMTSHR | |
| SCHEMBL7111926 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL22381380 | 0.77 | NPSR1 (0.48) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL24721488 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1NOTUMNPSR1 | |
| SCHEMBL24721395 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1NOTUMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1956949-A | Substituted sulfonamides | MERCK & CO INC (US) | 2007-05-02 | — | — | CN | disclosed |