Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721145 | 0.87 | AVPR2 (0.45) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL24721182 | 0.87 | AVPR2 (0.45) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL25061884 | 0.87 | AVPR2 (0.45) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL24721271 | 0.87 | AVPR2 (0.45) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL24721105 | 0.87 | AVPR2 (0.45) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL23717802 | 0.87 | SLC6A2 (0.43) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL19122068 | 0.86 | KMT2A (0.54) | ALDH1A1MEN1KMT2ASIGMAR1NOTUM | |
| SCHEMBL9480830 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL21210814 | 0.84 | SLC6A2 (0.43) | ALDH1A1MEN1KMT2AAVPR2OXTR | |
| SCHEMBL19204049 | 0.81 | CRHR1 (0.42) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919932-A | Biphenylamide derivatives as 5HT1D antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-07-06 | — | — | US | disclosed |