Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686044 | 0.90 | LOXL2 (0.39) | CHRM2CHRM1MAPTKMT2AALDH1A1 | |
| SCHEMBL27686029 | 0.87 | CHRM2 (0.40) | CHRM2CHRM1HTR6 | |
| SCHEMBL27686036 | 0.85 | CHRM2 (0.56) | CHRM2CHRM1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4881541 | 0.83 | MAPT (0.43) | CHRM2CHRM1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27686030 | 0.77 | CHRM2 (0.49) | CHRM2CHRM1MAPTKMT2AALDH1A1 | |
| SCHEMBL4883990 | 0.76 | MAPT (0.39) | CHRM2CHRM1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27686040 | 0.75 | CHRM2 (0.57) | CHRM2CHRM1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27705084 | 0.75 | F2 (0.41) | SMN1; SMN2F2ALDH1A1HTR6PTPN1 | |
| SCHEMBL4878959 | 0.74 | ALPL (0.40) | CHRM2CHRM1MAPTKMT2AALDH1A1 | |
| SCHEMBL4883077 | 0.71 | CHRM2 (0.41) | CHRM2CHRM1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087751-B | Process for preparation of 3-(2-hydroxy-5-methylphenyl)-n,n-diisopropyl-3phenylpropylamine | LEK PHARMACEUTICALS | 2011-11-02 | — | — | CN | claimed |
| CN-101087751-A | Process for preparation of 3-(2-hydroxy-5-methylphenyl)-n,n-diisopropyl-3phenylpropylamine | LEK PHARMACEUTICALS (SI) | 2007-12-12 | — | — | CN | claimed |
| CN-101087751-B | Process for preparation of 3-(2-hydroxy-5-methylphenyl)-n,n-diisopropyl-3phenylpropylamine | LEK PHARMACEUTICALS | 2011-11-02 | — | — | CN | disclosed |
| CN-101087751-A | Process for preparation of 3-(2-hydroxy-5-methylphenyl)-n,n-diisopropyl-3phenylpropylamine | LEK PHARMACEUTICALS (SI) | 2007-12-12 | — | — | CN | disclosed |