Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752999 | 0.86 | MAPT (0.59) | LMNAMAPTTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL13611646 | 0.83 | SLC6A7 (0.48) | HRH4DRD4LMNAMAPTTSHR | |
| SCHEMBL13611647 | 0.82 | KHK (0.43) | LMNAMAPTTSHRHSD17B10KDM4E | |
| Minozac Free Base SCHEMBL1752767 | 0.81 | MAPT (0.48) | DRD4LMNAMAPTTSHRSMN1; SMN2 | |
| Minozac Free Base SCHEMBL2799232 | 0.80 | TSHR (0.47) | DRD4LMNAMAPTTSHRSMN1; SMN2 | |
| Minozac Free Base SCHEMBL29369390 | 0.80 | TSHR (0.47) | DRD4LMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL1752927 | 0.79 | HRH4 (0.51) | HRH4MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1753200 | 0.79 | MAPT (0.47) | LMNAMAPTTSHRHSD17B10KDM4E | |
| SCHEMBL1752990 | 0.79 | KMT2A (0.51) | TSHRSMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL1753067 | 0.79 | ACHE (0.39) | HRH4LMNAMAPTTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087766-A | Pyridazine compounds, compositions, and methods | UNIV NORTHWESTERN (US) | 2007-12-12 | — | — | CN | disclosed |