Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635467 | 1.00 | LMNA (0.33) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL670101 | 0.90 | LMNA (0.35) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL2558960 | 0.89 | LMNA (0.36) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL4338288 | 0.86 | LMNA (0.36) | LMNAL3MBTL1TDP1AKR1B1 | |
| SCHEMBL21552110 | 0.84 | LMNA (0.39) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL999357 | 0.83 | ALDH1A1 (0.35) | LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL2559273 | 0.82 | LMNA (0.39) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL28758113 | 0.80 | USP2 (0.41) | LMNAUSP2 | |
| SCHEMBL7556267 | 0.80 | USP2 (0.41) | LMNAUSP2 | |
| SCHEMBL2635930 | 0.79 | GAA (0.31) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459599-A | Nucleic acid modulators of glycoprotein vi | REGADO BIOSCIENCES INC | 2012-05-16 | — | — | CN | disclosed |
| CN-1980947-A | Improved blood coagulation factor modulators | REGADO BIOSCIENCES INC (US) | 2007-06-13 | — | — | CN | disclosed |